Assoc Prof John Evans

Research Interests

Theme 6: The intersection of Nanoscience and Biology

We are examining the effects of micro- and nano-environment on cell growth and the result of mechanical forces on the cells which produce signals that regulate genetic expression. The studies take the form of developing bioimprints of cultured cells and then placing cell types or cell lines on the substrates that are produced. The types of growths that eventuate will be determined (proliferation rate, location, clustering, apoptosis, protein expression, gene expression). Studies will be performed with cancer and pituitary cells. In the cancers we are also studying the effects of hypoxia on the production of angiogenic and other factors. These cells also allow us to grow 3-D mirotumours as cell clusters which provide a further approach to understanding the effects of structural forces.

Post Doctoral Fellow

Kenny Chitcholtan

Research Students

James Dann, PhD
Siti Noorjannah, PhD
Lynn Murray, PhD
Baira Donoeva, PhD